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Nexavar (Sorafenib)

Sorafenib is a cancer medication that interferes with the growth and spread of cancer cells in the body. Sorafenib is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer. Sorafenib may also be used for purposes not listed in this medication guide.

Sorafenib is an anticancer medicine that is used to treat adults with kidney cancer (advanced renal carcinoma).This medicine is available only with your doctor's prescription.Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, sorafenib is used in certain patients with the following medical conditions:Advanced liver cancer.

Nexavar User Reviews

Average Rating: 3/10
Date: 2013-12-23 15:23:49
Reviewed by: Anonymous
User rating: 10
Nexavar for Cancer Involving the Kidney Cells: i lost my hair with the tretment and that was the only side affect i had.


Date: 2013-08-06 17:27:43
Reviewed by: Anonymous
User rating: 6
Nexavar for Cancer Involving the Kidney Cells: unfortunetly I came down with blood clots in my lungs as well as in the main artery. This situation was life threating and I was forced to stop taking nexavar. My cancer has subsided but am not sure the risk is worth the gain.


Date: 2013-07-20 04:33:51
Reviewed by: bgeorge9
Nexavar for Liver Cancer: Having numerous issues with it. First was blisters on the bottom of both feet. Doctor took me off of it for a couple of weeks and then started back at a quarter dose a day. I seem to only be able to handle 1/2 dose. Once I go beyond that my feet begin to hurt and I feel like the blisters are starting to come back. I do have daily nausea and weakness.


Date: 2013-05-18 09:14:32
Reviewed by: slg72
Nexavar for Liver Cancer: He had to stop working because of the Hand/Foot side effects due to the need to be on his feet all day.


Date: 2012-12-28 05:49:12
Reviewed by: Anonymous
User rating: 10
Nexavar for Cancer Involving the Kidney Cells: It is 12-03-09, I put a review in on 7-27-08. I am still on nexavar for advanced renal cell carcinoma and tumors are still gone. I still have problems with hand and foot syndrome. I forgot to add in my first review that my teeth became loose and my gums hurt and began to bleed. I had top and bottom partials so I had my teeth pulled and that took care of that problem. Also my hair started to fall out but it stopped and went into tight curls-has remained that way for 1 1/2 years. I am still a believer in the power of nexavar. It may not be for everybody but it is working for me.


Date: 2012-12-12 07:46:38
Reviewed by: wab1984
Nexavar for Liver Cancer: my mom just died of cancer just a few days ago ..so she was taking nexavar sorafenib 200 mg ...so i was buying these pills ..and are so expensive ..i have them because she didnt finish them ..so if anyone need them please contact me lucia_al16@hotmail.com


Date: 2012-08-02 03:11:35
Reviewed by: Trishkc
Nexavar for Renal Cell Carcinoma (Kidney Cancer): Worked well for several months, then stopped working. Was to be started on Sutent, but disease progressed too much. Had several courses of radiation for metastases.


Date: 2012-05-27 06:03:02
Reviewed by: fleetwood
Nexavar for Liver Cancer: Haven't started yet still waiting for the company to call


Date: 2012-04-01 20:47:44
Reviewed by: Anonymous
User rating: 4
Nexavar for Cancer Involving the Kidney Cells: i have the pain,swelling,blisters on feet and hands and cannot walk well the rash on back,frontand legs could not take the pain in feet any more had to stop using.


Date: 2012-01-04 16:21:45
Reviewed by: diana2help
Nexavar for Renal Cell Carcinoma (Kidney Cancer): working the node on my lung has shrunk from 1.4 cm to 1cm in just 3 months.


Date: 2011-12-29 12:01:37
Reviewed by: lastroseofsummer2
Nexavar for Liver Cancer: This worked for him for over a year, but then was not working anymore.


Date: 2011-10-05 21:00:47
Reviewed by: Anonymous
User rating: 10
Nexavar for Cancer Involving the Kidney Cells: Renal cell carcinoma..rt kidney removed w/lymph nodes, Dec 2008. On Sutent, ruptured my sigmoid colon. CT showed cancerous abdominal lymph nodes. Went on Nexavar Feb 2009. All the listed side effects (except heart attack)..diarrhea, nausea, mouth sores, hand & foot syndrome, rash from head to toe, hair (all head & body) gone.. very, very miserable. Took only 2 pills a day (half dose). P.E.T. scan in October showed the metastic lymph cancers were gone. Had my colostomy reversed Nov 2009. Going on maintenance dose (one per day) and hoping for the best.


Date: 2011-09-19 03:38:49
Reviewed by: marinette
Nexavar for Renal Cell Carcinoma (Kidney Cancer): very difficult because my back was destroyed in 1998 for which I had fusion of L4/L5. But it now hurts at the sacrum level. And I am very depressed.


Date: 2011-08-11 08:18:24
Reviewed by: Anonymous
User rating: 2
Nexavar for Cancer Involving the Kidney Cells: my husband has metastatic renal cell cancer, he started with tumors on his collar bone, esophogus, skull, lungs, diaphragm, and had right kidney removed. nexavar seemed to be keeping everything stable for about 3 years and the only side effects were diarrhea and a rash on hands and face which subsided after reducing the dose. for some reason unknown it had quit working and a bone scan revealed a new tumor growth eating through my husbands upper thigh bone. nexavar was stopped and he was put on chemotherapy drug Torisel, which seems to be keeping it stable so far but its only been 6 months.


Date: 2011-08-05 10:15:40
Reviewed by: Anonymous
User rating: 10
Nexavar for Cancer Involving the Kidney Cells: Had metastatic Kidney Cancer three years ago and had the left Kidney removed. Clean for two years until a brain CT revealed 12 small mets. Did three weeks of Radiation and put on Nexavar. Now a year later and still clean. Side effects passed after a time. Lost 65lbs, from 268lbs. to 203lbs. Very weak and tire quickly. It's getting better, however. I think it's working!. davemiller1590@yahoo.com


Date: 2011-07-22 01:45:44
Reviewed by: tmagee10
Nexavar for Liver Cancer: started in August of '10. Side effects pretty rough but have managed to stay at full dose 800mg per day. I am hopeing it will slow the growth down.


Date: 2011-04-15 14:45:57
Reviewed by: Anonymous
User rating: 10
Nexavar for Cancer Involving the Kidney Cells: RCC tumors have remained stable for over 2 years. Side effects are sore mouth, fatique, loss of appetite, and chickenpox type sores on legs, arms and upper torso. Squamous skin cancer also related to drug side effect. No growth in tumor size in over 2 years.


Date: 2011-03-11 03:50:21
Reviewed by: strangegurl
Nexavar for Liver Cancer: It hasnt been that hard on me as some others that have taken it. I was REALLY happy I didnt get the "Hand/Foot" thing. I do have quite a bit of fatigue and some sickness though. But so far, it seems to be working.


Date: 2010-12-17 17:52:14
Reviewed by: Phonefixer
Nexavar for Liver Cancer: I have been taking Nexavar for 2 1/2 years now at the max dose. The AFP went from 55,000 to 104 in 28 months. A nutrition product was taken also to relieve all side effects and help with the lowering of the AFP.


Date: 2010-11-10 03:03:55
Reviewed by: Becky from Kansas
User rating: 7
Nexavar for Thyroid Cancer: I have been on 800mg of Nexavar for thyroid cancer since 6-15-2011. Have had issues with the hand/foot blisters, thinning of hair, and diarrhea and blood pressure. My Oncologist has had me back off the pills several times to try and alleviate some of the blisters, but am off work and decided to just deal with it while off. As of 7-30-2011 the blisters have stopped, but I deal with the peeling and re-peeling of my skin. On blood pressure medicines now and have pills for the diarhea. No appetite loss, and thankfully no nausea. A visual inspection from my Oncologist approx. 1 month after beginning the treatment determined that the pills may be shrinking some of my tumors.


Date: 2010-09-30 09:42:38
Reviewed by: Tulliver
Nexavar for Liver Cancer: Too toxic - could not handle side effects. Hand-foot disease was rampant throughout my entire body.


Date: 2010-09-03 15:31:35
Reviewed by: sbtapdancer
Nexavar for Liver Cancer: My sister is just starting the drug this week or next. Liver transplant has been ruled out. Gathering info on how others responded.


Date: 2010-07-29 22:51:32
Reviewed by: mndaw
Nexavar for Liver Cancer: My doctor told me that the cancer marker has dropped significantly. But I had to take to lower the dosage from 800mg/day to 400mg/day due to the severity of the hand/foot reaction.


Date: 2010-06-16 15:41:59
Reviewed by: kaligirl77
Nexavar for Liver Cancer: So far so good... he's experienced diahreah and vomitting. We'll find out more in April when he has his next scan.


Date: 2010-05-23 10:18:02
Reviewed by: bapflum
Nexavar for Liver Cancer: had to discontinue after only 10 days due to side effects


Date: 2010-05-12 09:00:13
Reviewed by: Dottiepell
Nexavar for Tuberculosis (TB): havent started taking it yet 316


Date: 2010-02-07 00:41:07
Reviewed by: Anonymous
User rating: 10
Nexavar for Cancer Involving the Kidney Cells: Right kidney removed 4-21-06. CT 4-11-07 showed multiple tumors in both lungs. After approval from ins. co. started Nexavar on 5-15-2007. Had hand foot syndrome, sore mouth, constipation but tumors shrank in 3 mo and were gone in 6 mo.I was off work for 5 mo then went back to work as side effects backed off. It is 7-27-08 and tumors are still gone. I know nexavar works. It may not be for everyone but I was in good health until tumor was found in right kidney. My diagnosis is advanced renal carcinoma (Clear cell type).


Date: 2009-12-07 10:44:15
Reviewed by: 64ford
Nexavar for Renal Cell Carcinoma (Kidney Cancer): Nexavar is working for me,now it was not easy, within 3 week had side effects but with reseach and my doctors were able to handle them. One suggestion eat most important.


Date: 2009-10-18 14:22:52
Reviewed by: Anonymous
User rating: 6
Nexavar for Cancer Involving the Kidney Cells: Renal cell carcinoma..left kidney removed w/lymph nodes (Stage 4), 9/28/09. Start ECOG Clinical Trails, I believe I'm on Sorafinib. The side effect are: diarrhea, mouth sores, hand & foot syndrome, rash on my head, lossing hair, My feet are the biggest problem. I have multiple blisters on my feet that are very painful. I work at a desk job and can still work. If I had to be on my feet for work, I would not be able to work. It's still to early to tell if it's doing any good.


Date: 2009-06-12 07:20:00
Reviewed by: Litlsis
Nexavar for Liver Cancer: raised bilirubins too high had to stop


Date: 2009-05-29 06:28:00
Reviewed by: Anonymous
User rating: 4
Nexavar for Cancer Involving the Kidney Cells: have been on it for approx 3 weeks. how lonf before you know its working. my cancer is everywhere. responded to taxol well for about i yr. primary site unknown. docs felt it was kidney,liver or abdominal


Date: 2009-03-02 21:23:17
Reviewed by: 2 young 2 Die
User rating: 3
Nexavar for Hepatocellular Carcinoma: I've been on this medication now for 11 days and on the 10th day I got a bad rash on my whole body from neck to toe. I've stopped the medication and will continue when the rash goes away. I also have had my blood pressure raise quite a bit. I don't really like the way the medicine makes me feel but if it will give me a few more years on this earth I guess I can make a go of it!


Date: 2009-01-16 19:47:47
Reviewed by: dhkling
Nexavar for Renal Cell Carcinoma (Kidney Cancer): Side effects were too great to continue treatment



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